Sclerostin (Sost) and dickkopf (DKK-1) are two protein that inhibit LRP 5/6 from activating this pathway, leading to degradation of -catenin by GSK-3
Sclerostin (Sost) and dickkopf (DKK-1) are two protein that inhibit LRP 5/6 from activating this pathway, leading to degradation of -catenin by GSK-3. analogs represent the only anabolic realtors approved in both US and European countries currently. Strontium ranelate can be an extra agent obtainable in Europe however, not the united states which has both…