Three significant points should be emphasized: 1) immunosuppressive and anti-viral effects of CsA are possibly independent [161, 162], 2) inhibition of cyclophilin is a potentially useful strategy for reducing HIV-1 infectivity and replication and isomerization of the – Gly-Pro- angle in Ace-His-Ala-Gly-Pro-Ile-Ala-Nme [190]
Three significant points should be emphasized: 1) immunosuppressive and anti-viral effects of CsA are possibly independent [161, 162], 2) inhibition of cyclophilin is a potentially useful strategy for reducing HIV-1 infectivity and replication and isomerization of the – Gly-Pro- angle in Ace-His-Ala-Gly-Pro-Ile-Ala-Nme [190]. Gly-Pro motif in the N-terminal domain of HIV-1 capsid (CA) protein. In…