Trastuzumab (T; 10mg/kg intraperitoneally in sterile H2O double weekly) and pertuzumab (P; 12mg/kg intraperitoneally the initial week and 6mg/kg intraperitoneally in 1% sterile PBS every week) had been supplied by Genentech (SAN FRANCISCO BAY AREA, CA)
Trastuzumab (T; 10mg/kg intraperitoneally in sterile H2O double weekly) and pertuzumab (P; 12mg/kg intraperitoneally the initial week and 6mg/kg intraperitoneally in 1% sterile PBS every week) had been supplied by Genentech (SAN FRANCISCO BAY AREA, CA). intermittent administration (2 weeks on/off), and decreased dosing (1/2 dosage) was also looked into. Inhibition of tumor development, downstream…