O-methyl-serine dodecylamine hydrochloride (MSDH) is a detergent that accumulates selectively in lysosomes, a so-called lysosomotropic detergent, with unexpected chemical properties

O-methyl-serine dodecylamine hydrochloride (MSDH) is a detergent that accumulates selectively in lysosomes, a so-called lysosomotropic detergent, with unexpected chemical properties. membrane. When transferred to cell culture conditions, the ratio between MSDH and plasma membrane lipids must therefore be low, at physiological pH, to maintain plasma membrane integrity. Transmission electron microscopy suggests that MSDH vesicles are

em class=”salutation” To the Editor, /em We read the article written by Lin et al with interest and would like to share our opinion on it

em class=”salutation” To the Editor, /em We read the article written by Lin et al with interest and would like to share our opinion on it. infections. Ageing presents structural and practical loss influencing the entire system and exactly, the immune system. 3 Thymus hypoplasia and the gradual decrease in both function and quantity of

Supplementary MaterialsSupplementary Table 1: Proteins reported in literature versus this study ns-2040056-028-suppl1

Supplementary MaterialsSupplementary Table 1: Proteins reported in literature versus this study ns-2040056-028-suppl1. respective lane. ESI-LC-MS/MS, electrospray ionization-liquid chromatography tandem mass spectrometry. ns-2040056-028-suppl4.pdf (4.8M) GUID:?06AE5FC0-98B0-4785-BD46-91D9C625BA6A Supplementary Fig. 2: Comparative profile of the intervertebral disc nucleus pulposus tissue on a 10% sodium dodecyl sulfatepolyacrylamide gel electrophoresis after sample clean-up using: acetone; methanol-chloroform; 3-kDa membrane cutoff device. (A)